It seems that there are more of us out there that could use some advice. Also, my mother could barely walk due to advanced pain in her legs. The more active you are, the more you will benefit. Limit Sweets Too much added sugar —sugar that is put into foods, not the naturally occurring sugar found mainly in fruits and dairy—raises blood pressure and cholesterol levels, according a review in the journal Open Heart. This involves uncomfortable pressure, squeezing, fullness, or pain in the center or left side of the chest that can be mild or strong. As to statins what would you say to someone who has FH?
But how many pills do I need to live? Only the Lord really knows, but I will be selective. You should be too! Save the Olive Oil for salads and adding to. I am so stressed over all the conflicting stuff I am reading. Although I have a pretty healthy diet and lifestyle my doctors and lipid clinic are convincing me that I have hyperfamilial cholesteromia and will be at great risk if I do not take statins.
I have resisted until now but began taking them t three weeks ago. I either have flu or the statins are giving me the symptoms of it — feel ghastly. I also have high Lp-pla2. A nutritionist got my levels down last year but not enought say the docs. Helen I know what you are going through. Too many varying opinions. One thing I do know is that if you take a statin or even a beta blocker you must take a COQ10 supplement.
You need a high quality supplement of it to prevent heart problems like mine. I found out too late. My next and last option is a transplant. Thanks to the drug companies. Best wishes in your health! My mother is almost She had the high cholesterol, high triglycerides and BP for years. She is in deep dementia now, delusional.
The only reason I went back on a low 10 statin is I had a heart attack at 47 and the doctors put extreme pressure on me. My numbers are better, but will it really keep me from having a heart attack? Probably not, as I am an emotional eater.
I am watching my D, C. I just got tired of fighting the medicos. But 10 is the limit. A major risk factor in heart disease seems to be family history. Just saw your comment. My mother passed on March 30th of Dementia Behaviors. My own father died at 50 of Congestive Heart Failure, but 1, He smoked most of his life, 2, He probably had what we now call Bipolar, took old fashioned tranquilizers and had high blood pressure.
I believe my heart attack was caused primarily from marital stress, self-medicating for Degenerative Disk Disease, and just had started Paxil. Although my cholesterol was somewhat high, many people have high cholesterol without having a heart attack.
I am too heavy and am not able to get much exercise where I live. We are evaluating a better place to live now that my mother is gone and we can be more flexible. We like to spend time in NM where my husband packs with goats. Thank for your interest…and OH! I just went back on 10 Lipitor after getting off again…I still am confused! My total cholesterol hovers around — even though I eat fairly healthy — fish, chicken, veggies, very little processed food or carbs, in general.
However, the company I work for has guidelines we have to meet for our health insurance. One of those is that my total cholesterol has to be below I take Crestor and it keeps my cholesterol around — Thank you so much DM!!! Seneff really great video. I eat fish oil pills three times a week nothing else. I have apples every day, Spinach, olive oil, yogurt with blueberries.
Tilapia, sardines from Canada, chicken breasts, avacado, almond butter, almond milk, onions sweet potato, also do intermittent fasting and I do interval training for 35 minutes three times a week. Your diet and lifestyle intermittent fasting and interval training sound pretty good actually.
One thing I would suggest for you to try for the cholesterol would be krill oil combined with coconut oil — on a daily basis. I would take at least grams of krill maybe more and at least a tablespoon of coconut oil a day.
You may need to build up on the coconut oil and start with a teaspoon, but you should be able to at least build up to a TBSP and you may actually need much more depending on your unique metabolism. I take TBSP a day for example of coconut oil and my body loves it but I know that would be way too much for some people. As I said everyone is different. They work synergistically together and both enhance each others activity in the body.
I know of people who simply could not lower their cholesterol with anything until they tried krill oil and suddenly it dramatically lowered.
So it is worth a try to replace your fish oil with krill oil — it is a little expensive, but much less expensive than drugs.
You can eat the coconut oil in several ways, such as in a smoothie or even cooking your eggs in it — but find a way that is palatable to you or else you will soon get sick of it and stop eating it. I mostly eat my coconut oil in a coffee smoothie I make every morning actually and it works great. Also, there are specific supplements that help with cholesterol levels, such as tocotrienols, niacin, enzymes, and astaxanthin. And you need to also make sure your gut flora is balanced.
That means fermented foods and probiotic supplements — extremely important for all aspects of health including cholesterol balance. Note, unless the yogurt is homemade it does NOT count as a fermented food, but kefir does.
You could try some organic goat milk kefir for example with a little stevia, it is delicious and a great source of probiotics. Fermented coconut water kefir would also be a great choice — which you can easily make at home — and its cheap, you can get all you need for about dollars a week. The kefir starter is a little expensive, but not too bad and will last for a quite a while — I would suggest Donna Gates kefir starter for coconut water.
Again, try to find a good naturopathic doctor who really understands cholesterol issues and how to manage them with nutrition, supplements, and lifestyle. A conventional doctor will typically not be able to help in these areas and will only resort to drugs.
I would also make sure to look up Dr. David Brownstein and listen to one of the 30 minute to 1 hour lectures on the thyroid and make sure the specialist you go to is in line with what Dr. Sean, first it is important to realize that the dangers of high cholesterol are way overrated. In fact high cholesterol has been shown in many studies to be healthier than low cholesterol. I can give you plenty of references in the medical literature if you want them.
The demonization of high cholesterol mostly comes from the pharmaceutical industry because statins are the 1 money making drug in the world.
Statins literally make billions of dollars for big pharma. There are many highly questionable studies funded by big pharma that supposedly show a relationship between high cholesterol and heart disease.
However, there are so also many very solid studies not funded by big pharma that show the opposite. In my opinion you should absolutely not take statins, they are way too poisonous. See this interview with Dr. Also see my post above where I list the catastrophic damage caused by statins. I would be very weary of conventional doctors, they are very ignorant about how to actually solve chronic health problems and almost always only resort to one thing: It is sad but true.
I would find a naturopathic doctor who actually understand nutrition and not just drugs. Second, you need to try to figure out why your cholesterol is so unusually high.
It is high for a reason and it may be genetic hypercholesterolemia or it may be something else, such as a thyroid problem. Please realize that just because your thyroid panel came back normal in no way means your thyroid is ok.
Please look up Dr. David Brownstein online and listen to his lectures to understand that most doctors simply do not understand thyroid problems and do not understand how to diagnose subclinical thyroid problems. You again need to avoid conventional doctors and find a doctor who actually understands subclinical thyroid problems. If you try to handle this problem with a conventional doctor you are going to end up on a lifetime of meds and drug cocktails.
There are many lifestyle and dietary things you can do to balance your cholesterol. Your diet sounds ok, but only ok — not very healthy. You need to become your own health expert and begin reading about what is actually healthy and what is not. For example, do you consume fish oil or olive oil or coconut oil?
Are you eating any fish? Are you eating any fermented foods? Is your gut flora out of balance? What are your D levels? Do you take magnesium, iodine, turmeric, astaxanthin, tocotrienols, enzymes? Are your hormones out of balance? Are you eating too many omega6 oils and not enough omega 3? Are you consuming enough fiber? A grass fed steak may be the very thing you need to start eating. Eggs are great if they are from the right source and cooked the right way — if you are eating scrambled over cooked non organic eggs that is bad.
The yolk should be as raw as possible and the white should be cooked. You should do some reading and understand why. Chia seeds and quinoa are good, but it is better so soak the chia seeds before you eat them — should do some reading to find out why. Realize that there are many myths about what is healthy and what is not and that everyone is different. Some people need a lot of fat and protein and some people need a lot of carbs vegetables, not starch. You need to figure out what works for you.
A conventional doctor will absolutely not be able to tell you what a healthy diet is. You have to take control of your health and that requires education. I would begin reading sites like mercola. There is a lot to learn and it is complicated but you can do it, the resources are available — take the time to start learning.
The conventional medical industry is run by corporations interested in profits not your health, primarily big pharma. In general, doctors do NOT know what is best, there are exceptions but it is rare. Start reading, start listening. Find a qualified naturopathic doctor who specializes in nutrition and cholesterol and stay away from conventional doctors.
Its your life, its your choice. I stumbled upon this chat and really appreciate your comments. I have a calcium score of My doc put me on Crestor 2 years ago. Do you think it is possible to reverse my arterial calcium? I thank you in advance!
David, sorry to be replying just now, I just noticed your question. The answer is absolutely yes! Its great that you got off of the poisonous statins. Please read this thread to understand real ways of improving cardiovascular health. For the calcium issues, there are many nutrition and lifestyle interventions. Sufficiency in D3, K2, and Magnesium is a first step. Stop taking calcium supplements if you are — or change to a plant based form. You can break up the calcium by using supplements like MSM, chanca piedra, gravel root, citric acid, and enzymes.
The main theme of this book is to heal calcification. This book should give you all of the knowledge you need to completely reverse and heal your arterial calcium issues. Thank you David and Glen. My cousing had her thyroid removed and my grandma takes medication for her thyroid.
He said he thinks it might be familial hypercholesterolima. He also is having both my parents come in for a cholesterol check before he puts me on Statin. I work out 4 times a week cardio and strength exercises.
My Dad and his sister have high cholesterol, but not at my age. My meals are generally the same. I eat a spoon of almond butter, maybe eggs or oatmeal for breakfast. Lunch is chicken with quinoa or yogurt with chia seeds and banana or apples.
Dinner is salad and more chicken with hummus. Excuse the grammatical errors. Sean, sounds like you could have familial hypercholesterolemia high LDL due to a genetic mutation. Sean I would get a full thyroid panel done including antibodies.
Low thyroid can cause high cholesterol. Is this true for Familial hypercholesterolemia too? M cholesterol runs between 6. I have been useing 4S slimming pills now for 3 weeks. Just lost 3 kilos in the first week. I cant sleep at night and im irritated. My skin is in a horrible condition. Its now 3 days that i dont use it anymore. Im feeling sleepy the entire day and nervous and drunk in my head and like death warmed up.
Still struggleing to sleep. Thats after i read that 4S doesnt have side effects! I havent felt this crap in years and im wondering what junk in this pills cause my symptoms.
I will never use it again. The role of lipid peroxidation in promoting atherogenesis, arguing that its effects are more pronounced on PUFA than on SFAs or monosaturated fatty acids.
Evidence that potentially carcinogenic preservatives in processed meats as well as high-heat cooking methods have influenced perceptions that red meat per se has adverse health effects. The hazards of diets with increased carbohydrates as a result of being lower in fat, in low-fat diets followed to improve health, especially cardiovascular health. It is time to reevaluate the dietary recommendations that focus on lowering serum cholesterol and to use a more holistic approach to dietary policy.
And that is what Doctors do, treat symptoms, not underlying causes. To be fair, most people are not going to change their diets drastically as some of us have, to get better results. He was headed towards diabetes, but with a modified Paleo diet giving up most grains , his blood sugar is now normal.
But I still worry about what the statins are doing to him. And he loves to brag about how low his cholesterol is compared to mine. And truthfully there are too many people that are totally fine with just popping pills for whatever ails them without ever making any effort to modify their diet, increase their exercise, lose weight, and reduce stress. Too many doctors still erroneously buy into the cholesterol is bad myth and are only focused on getting the numbers into target range.
Even for people at with CAD there are many holistic approaches that have few if any side effects. Statins do have some anti-inflammatory effects which can benefit people with CAD beyond the lipid lowering effects but so do many common herbs, spices, and nutritional supplements in addition to clean living.
Travel makes it hard, especially outside the US, but not impossible. Most restaurants will make substitutions if asked, especially since it seems almost everyone is on some sort of restricted diet these days i. We do it ALL the time! Also, your husband could request a fridge in his hotel room hotels will upon request for diabetics to store insulin then he could bring or buy food items such as fresh fruit and maybe have a healthy protein shake instead of the free continental breakfast of bagels and pastries offered at many hotels.
This is a very informative article. My uncle is taking a Statin. We spend so much time reading about healthy living instead of just figuring out what works best for us. All in all,great piece Chris! I am not sure why you are referring to an outdated Cochrane review from regarding primary prevention using statins. Ref No 7 in your article. The most recent Cochrane review on this was published in Jan See http: It clearly concludes after reviewing several new trials: There was no evidence of any serious harm caused by statin prescription.
Evidence available to date showed that primary prevention with statins is likely to be cost-effective and may improve patient quality of life. Reductions in all-cause mortality, major vascular events and revascularisations were found with no excess of adverse events among people without evidence of CVD treated with statins. This runs contrary to what you are proposing-Maybe for the sake of objectivity you could edit your article to include the latest Cochrane review which DOES show that statins can be of use in primary prevention of heart disease.
Broadening the recommendations in cholesterol lowering guidelines to include statin therapy for low risk individuals will unnecessarily increase the incidence of adverse effects without providing overall health benefit.
John C Check out the anecdotal evidence of statin side effects. Most physicians deny that aches and pains clearly listed as possible side effects are attributed to old age, even on year olds.
One of the newest possibilities is increasing the risk of diabetes. ALS is also suspected since it is increased in those taking statins. It does seem to me that many doctors see that statins should be the first treatment for anything to do with heart disease. When I was diagnosed with Type 2 diabetes I was prescribed statins along with metformin rather than the option of lifestyle and diet changes. Too many doctors skip the diet and lifestyle talk and simply go straight to the meds.
People seem to want a quick and easy fix without having to change anything. Just eat antioxidant rich foods people! This is just what I needed to send to some friends on family on the topic.
Sadly, many I know would rather take a pill the doctor says is great than change their eating patterns. He was discharged from the hospital on 80 mg. With the aforementioned lifestyle changes and statin therapy, in a matter of 2.
We were really worried about that extremely low number. I felt it was dangerous and worried about the other health consequences, although his cardiologist was thrilled with that LDL number! This seems to be why they are being considered as possible therapies for other diseases including prostate cancer, among others. He currently eats an anti-inflammatory, low carb, diet, with variety of fresh vegetables, fruits, healthy oils and nuts, natural meats and no sugar or processed foods.
He takes several supplements such as Ubiquinol, magnesium, fish oil, resveratrol, aged garlic, and B complex to name a few. We both hope that he can get off the atorvastatin completely. The sad thing is that his primary care doctor never really counselled him on lifestyle changes and instead just wanted to put him on meds lovastatin.
I think he would consider trying RYR again in lieu of statins, especially if there are possible other health benefits from using such a supplement. Do you know of any good studies that show that RYR has the same beneficial anti-inflammatory effects? Would be interested on your thoughts since he would likely benefit.
I believe those cholesterol numbers are WAY too low and dangerous. There are actually many studies that show people with high cholesterol liver longer than those with low cholesterol.
Not that high cholesterol is healthy, but many studies show it is healthier than low cholesterol. I can give you some references if you want.
The idea that aspirin is somehow healthy and a good way to prevent a heart attack is insanity. It would be much better to thin the blood with healthy omega 3 oils preferrably from wild caught fish or krill oil or fermented fish oil. Aspirin is a potent cox-1 inhibitor which damages epithelial cell structure. This leads to gut lining damage and to intestinal bleeding, which can be deadly.
As a cox-1 inhibitor, aspirin also damages blood vessels by disrupting the epithelial cells that line the vessel walls and can lead to blindness for example because the vessels in the eyes become leaky leading to advanced wet age-related macular degeneration — leading to blindness.
Taking aspirin daily to prevent a heart attack is utterly ridiculous and serves only to line the pockets of pharmaceutical companies and deteriorate your health. Most doctors are just so ignorant it is the only thing they can offer. Find a good naturopathic doctor and stay away from conventional doctors unless it is an emergency. Here is list of the most important things for cardio health: D-Ribose and Acetyl L Carnitine are also beneficial.
Avoiding sugar and heated, damaged, rancid fats is also very important. David Brownstein has an excellent book on thyroid health and its importance for cardiovascular health — which does not seem to be widely known. Herbs that are helpful: And the list can go on and on — in other words there is so much that nutrition has to offer and when used skillfully it will be much more effective and safer and healthier than drugs will ever be. When the body is sick it is not deficient in a drug as doctors seem to act like.
Most drugs dont heal root causes, they suppress the warning system of the body by suppressing symptoms which is highly deceptive and misleading and destroying the lives of so many people. I am 56 and recently suffered a near fatal MI. So there is a lot of hope! It requires a lot of research, commitment, expert guidance if you can find it, and money!
Eating all organic foods, high-quality oils, grass-fed meats and wild fish, etc certainly increases your food budget, along with all of the supplements and detox tools but the cost is nothing compared to what prescription drugs and medical care costs.
Best of luck to you both. What causes tiredness when taking a statin? Chris, I remember watching a Video by Dr. Are there classes of statins that can modulate LDL-P? This would seem to be a good use if there are not too many side effects or other treatment options. What if you never have had heart issues, yet have Diabetes and Rheumatoid Arthritis?
Doing Paleo — hba1c coming down all the time — down to 5. On Enbrel and small dose methotrexate — no diabetes drugs. Your CRP is excellent and your A1c is improving.
Could eating paleo and eating lots of fats like coconut,avocado,macadamia nuts be raising some of those numbers? The trials supporting these numbers are referenced in the guidelines.
I believe this is where the recommendation stemmed from. I would not argue with recommendation if the patient has failed LSM in the past.
I noticed that you have Choleast in your web store, and I wonder what your thoughts are on the appropriate use of red yeast rice RYR. I know all about the RYR controversies regarding safety and efficacy monacolin content, citrinin, etc. But assuming that you have a good product Choleast and others have been shown to have significant amounts of monacolins and insignificant citrinin levels , at what point would you use the RYR as an intervention?
There have been quite a few RYR studies showing benefit, and some e. Several of the RYR researchers surmise that the other components in RYR other monacolins and phytochemicals besides the monacolin K are working together synergistically to reduce risk in a way that isolated monacolin K cannot do, even though the actual LDL number is not reduced as much compared to a statin drug. My conclusion was similar to yours: Some studies have shown that RYR in conjunction with other therapies e.
What is your response to the notion that cholesterol is produced to repair endothelial damage caused by inflammation caused by poor diet? Am I understanding you correctly? Are these two views at odds or do they work together? Chris, thanks for following these issues and enlightening enlightening us. Coukd you please answera stupid question? How do these studies know that a statin prevented a heart attack or stroke?
A randomized trial separates participants into two groups. One group receives statins, the other receives a placebo. They follow the groups for a while and record cardiovascular events in each group. If the statin group has fewer events like heart attack , and other factors that could have influenced the outcome were adequately controlled for, then the assumption is that the statin reduced the incidence of the event.
I have LDL particles on a Paleo diet and am now resuming a low fat regimen to see if that helps. Thank you for your commitment to both outstanding research and communication! I believe you are a life saver. Paleo with a higher intake of carbs and lower intake of saturated fat. It is generally effective in reducing LDL-P.
Hi Doc, I have it full on! Without meds my family has numbers of 12 and I embarked on ketogenic diet in and astounded my doctors. It came down to 6 total cholesterol. None in my family can tolerate statins we WILL die of kidney failure and quickly too. I feel our ilk have been done in when it comes to research. No-one has looked deeply into our plight. I wish I knew how to start a fund and get some scientists on board to really study it.
My heart is solidly broken by this, yet the females live to over He too cannot use statins for even 2 days. NONE of the statins. I feel a little angry too and helpless.
I would appreciate some guidelines for that. Took your whole High Cholesterol Action Plan, expecting to get them. One more test to get back. I know increasing safe starches and reducing saturated fat and cholesterol are key my cholesterol was kept in check as a vegetarian but shot through the roof on paleo.
How often is red meat OK? Eliminate raw dairy completely? Really baffled about the specifics. I appreciate all the info I did get and the other specifics but thought that section could be be detailed. There is rarely if ever a single criterium that guides a treatment decision, especially with a condition as complex and multifactorial as CVD. Instead of relative or absolute risk these studies should have to use some kind of expected life extension amount.
What I mean is that no medical treatment can prevent death, only delay it. I think this would give a more easy to understand benefit. Malcolm Kendrick has used something like it in his books. If people have a heart attack in 5 years on placebo they should see how long it takes for people to have a heart attack in the statin group.
From this you could calculate the expected life extension in the experimental group. Then the question becomes would you risk all the side effects to extend your life for 60 days? At best, they only delay it. So from this perspective, the real meaning of 1 in lives will be saved is that if one man at high risk of heart disease took a statin for one year, he would expect to gain an additional two days of life.
So if we put this another way, if a year-old male at very high risk of heart disease took statins for 30 years, he could expect to live an additional two months on average.
Where do favorable studies on statins come from? I believe they are essentially all funded by those who financially gain from positive outcomes, e. This conflict of interest immediately calls into question the real validity of these studies. Statins work by suppressing an enzyme in the liver that interferes with cholesterol production.
However, this enzyme, HMG Coenzyme-A reductase, is not only needed for cholesterol production, it is also needed for several other fundamental biological processes, including production of one of the most essential nutrients that the body needs, which is Coenzyme Q10, an incredibly important nutrient especially for cell energy and heart health. HMG Coenzyme-A reductase is also needed for producing selenoproteins that are the backbone antioxidant system of defense for every cell in the human body, required for healthy immune function, and primary activators of thyroid hormone.
The cholesterol pathway that HMG Coenzyme-A reductase is needed for is also linked to the production of vitamin D, adrenal hormones, and sex hormones. It also makes many gene-signaling molecules in the isoprenoid family that are required for healthy cell function and the prevention of cellular mutation cancer.
All of these processes are indiscriminately interfered with by statins, which is potentially devastating to human health. The risks can increase along with the dosage. So, statins deplete CoQ10 and thus cause cardiovascular problems the very condition they are supposed to be helping. They cause fat to be dumped all over the body in places it should not be. Statin use is also associated with copper, zinc, vitamin E and severe selenium depletion. Statins have been linked to intense and debilitating muscle pain, kidney failure, liver dysfunction, and cataracts.
Some people have reported severe memory loss as cholesterol is very important for brain function. There is also clear evidence that statins cause high blood sugar, which is sometimes mistaken for type 2 diabetes.
Statins are also associated with an increased risk of developing type 2 diabetes. In fact, a recent study http: This implies statin drugs which are meant to lower heart disease risk, can actually massively increase heart disease risk.
In fact, statins have been found http: Forcefully lowering cholesterol can also cause major hormonal imbalances cholesterol is a precursor to ALL sex hormones which then causes a long list of health problems.
Furthermore, one main reason cells make cholesterol is to repair themselves. This is especially important for nerve cells, which do not split and divide like other cells in the body and therefore must repair themselves in order to survive. The receptors on nerve cells enable them to receive neurotransmitters, thereby enabling a person to have cognitive function and memory.
These nerve cell receptors require cholesterol as part of their proper three-dimensional structure. Statins interfere with this process as an undesirable side effect, inducing slow and progressive memory loss the longer they are used — a form of slow poisoning of your brain. If asked about memory loss after being on statins for a few years doctors will just blow it off as aging. Most doctors do not understand what they are doing to people.
Statins do NOT EVER address root causes, they mislead a person into thinking they are ok because of a better number, but in reality the underlying cause is never addressed and sometimes made worse — very very deceptive as are most drugs. I really wish chris that you would have taken a much harsher stance against statins than what is written in this article, but at least you are somewhat negative about them and I know you cant please everyone: I believe within a few more years statins will be off of the market and no longer sold once it is realized the catastrophic damage they are doing to people — just my opinion.
You have a greater risk if you have a close family member who had heart disease at an early age. What can I do to lower my risk of heart disease?
Fortunately, there are many things you can do to reduce your chances of getting heart disease: Control your blood pressure. High blood pressure is a major risk factor for heart disease.
It is important to get your blood pressure checked regularly - at least once a year for most adults, and more often if you have high blood pressure. Take steps, including lifestyle changes, to prevent or control high blood pressure. Keep your cholesterol and triglyceride levels under control. High levels of cholesterol can clog your arteries and raise your risk of coronary artery disease and heart attack.
Lifestyle changes and medicines if needed can lower your cholesterol. Triglycerides are another type of fat in the blood. High levels of triglycerides may also raise the risk of coronary artery disease, especially in women. Stay at a healthy weight.
Being overweight or having obesity can increase your risk for heart disease. This is mostly because they are linked to other heart disease risk factors, including high blood cholesterol and triglyceride levels, high blood pressure, and diabetes.
Controlling your weight can lower these risks. Eat a healthy diet. Try to limit saturated fats, foods high in sodium, and added sugars. Eat plenty of fresh fruit, vegetables, and whole grains. The DASH diet is an example of an eating plan that can help you to lower your blood pressure and cholesterol, two things that can lower your risk of heart disease.
Exercise has many benefits, including strengthening your heart and improving your circulation. It can also help you maintain a healthy weight and lower cholesterol and blood pressure.
All of these can lower your risk of heart disease. Drinking too much alcohol can raise your blood pressure. It also adds extra calories, which may cause weight gain.
Right away my HDL soared to 67 within 2 months which was great. I always had a high carb, low fat diet and was always puzzled why everything was normal except my HDL which was under Now a year after being Paleo, my results are not so good.
But what was concerning was that my small diameter LDL was 56 and over 40 was high risk. The very thing Paleo is supposed to reverse? So maybe I went to much to the other side and getting an NMR profile done for baseline peuposes.
I have been where you are Rory. After about 8 months on Paleo, my cholesterol went up to It seems I need the carbs because my thyroid TSH was higher at 4. Maybe hypothyroid is going on here for me, and I am slim at almost 10 stone so the doctor does not recognise a problem. I am trying the Ray Peat way this last little while and am hoping to get my numbers re-tested soon, and hope they are better. Are you actually surprised that eating more animal fat and protein was going to do anything but adversely affect your cholesterol?
Looking at all these LP-IR scores — mine is I have a father on dialysis and an older brother who is diabetic. I know I have the potential to become diabetic because I monitor my blood sugars and have seen some crazy numbers and fluctuations. This worries me a bit. This is a great article about heart health. But I would have liked to see some mention of oral health. There have been hundreds of studies done linking oral health and heart disease.
If you improve your oral health, your outlook for heart disease is much better. A product such as the Beam Brush can improve your oral health literally before your eyes. Find out more at http: Do you have specific recommendations about the type of meat people should be eating? There is so much contradictory information out there, hard to know what to believe.
I have been on a low carb diet for 3 years now and on Paleo for about 6 months now. So what is the answer? It seems there is no definitive answer for the high LP a. The more I read about this the more confused I become.
I think the treatment to bring down LP a is more risky that just leaving it alone, especially if you have pattern A LDL. I suppose I could be wrong about this but there is really no one for me to turn to for answers.
Thank you, Chris — you have directly and concisely answered the question I have had for a year. Now to figure out how to transition to Mediterranean Paleo — I already eat a fair amount of fruit and starch, and mainly have to reduce dairy fat.
What a great post, I wish the mainstream media would offer solution orientated advice like this! A few years ago I was told I had a high risk of heart disease due to my weight being out of control. This was the catalyst I needed to turn my life around; through physical activity and eating healthy my life has completely flipped. My question is this: Maybe a closing chapter regarding cardiovascular disease detection would be useful.
What other viable detection methods are there that a layperson at risk with a high LDL-P could pursue with their MD before an entire lifestyle change is made or statins prescribed? The associated high blood serum cholesterol is an attempt to partially correct for this defect. The essay is hypothesizing. I am absolutely thrilled to say I do every single one of these things.
I am so happy my mother instilled such good habits in me at such a young age! It is something, but it is small. For patients needing just a little help, this seems like a good option. Another option I came across is Red yeast rice. One study found that 2. Apparently it contains Lovastatin, but in a much lower dose than is used in Statin therapy.
Finally, I found a little bit of info about Berberine, which is mostly used in combination with Red yeast rice, but seems to have effects by itself too.
For someone with further to go, adding these small effects together could be an effective option. We have been trying to do a more Mediterranean type paleo diet, but it takes some time to undo the WAPF approach that I have been using for the past 13 years, as it works well for me, but perhaps too high in sat fat for him Anyway, he started 1. Do you know anything about the mechanism of action for the berberine?
I have read that is really helps with blood sugar control, but just wondering how that works on a physiological level.. The title talks about prevention and reversal of coronary artery disease, but i did not see anything that directly discussed reversal. For example, for reversal do you need to be at a lower LDL-P level than for prevention? Should you rather follow one dietary approach over another for reversal? An overall question remains as to whether it can be reversed.
While improvement in IMT has been shown, there is no similar consistent data with regard to coronary arteries that I am aware of. Is the second one supposed to be LDL-C? After going paleo, my cholesterol and LDL-P skyrocketed. I am otherwise healthy, except I need to use bioidentical sex hormones. I am going to adopt a more Mediterranean paleo diet, add more soluble fiber, and learn about which foods to eat containing more monounsaturated fat than saturated fat.
You are a blessing! Chris, Thanks so much for this great series. In your practice, have you noticed that reducing a certain type of saturated fat yields better results for people with genetically-driven high LDL-P? After reading this post, I feel a sense of satisfaction to all my sacrifices for a healthy lifestyle. Great posts on CVD!
Thank you very much for your work and mainly for share your knowledge! Are there particular foods you would recommend for this?
So far, it seems like sugar and polyunsaturated oils are the only things that succeed in making me gain weight, but I know that is not good. It is certainly not good for heart health, as your post explains. Any advice would be appreciated. I can definitely relate! How is your gut health? In the absence of other health issues or high levels of chronic stress, I think to gain weight you probably just need to eat more food! Dairy too, if you tolerate it well. People who are overweight can lose and people who are underweight can gain.
And Alyssa is correct. Eat more fat — healthy fats — definitely. Eat real whole nutritious foods. I was blessed with a Fibromyalgia diagnosis and you can heal the body. In fact, there was a recent Success story at MDA about someone who gained healthy weight months after starting Primal. You can search that, too. Thanks so much for your advice!
And I have been trying to do more gut friendly eating. I started fermenting vegetables, and my my digestive tract has really improved. They taste better than macadamias, imo. Cashews have much lower n-6 than almonds, but are not nearly as low net carb as most nuts. Thank you very much for this. I was wondering what natural therpaies as mentioned under genetics you have found to be effective to reduce LDL particle number.
Are one of these more accurate? There are several nutrients that do affect cholesterol levels in most people; soluble fiber is one example, and vegetable oil is another.
I understand there is an effect but was trying to get a clearer idea of how it worked. If most of the cholesterol in you bloodstream is being created by your body in response to some need, how does a food item raise or lower it? Is that your term used exclusively for people who are hypercholesterolemic?
A former colleague of mine was truly hypercholesterolemic. Both are on lipid-lowering drugs. Years ago while experimenting with a LCHF diet it went up to 6. A low fat vegetarian diet brought it down to In my case saturated fat most definitely raises my cholesterol. Given my numbers and how my body responds to saturated fat would you define me as a hyperresponder? What you said about cholesterol is totally false and you need to review a complete study. Cholesterol in the diet does impact blood levels but below the to levels that so many studies like to look at.
Well, it appears it is important what you eat if that is the case. What about reversing heart disease for the majority of adults that already have it? The Paleo diet is a sham and does not reverse heart disease. Most adults would do far better studying Drs Ornish, Esselstyn, Fuhrman and others that focus on whole plant-based diets.
AND all my sex hormones are super low, and cortisol is high. Chris, one good source for mono-unsaturated fats you may not be aware of is purified Omega 7. Why do you suggest that they increase it here? Because low-carb diets induce insulin resistance.
This is normal and totally necessary in the context of a very low carb diet. Is his view on insulin sensitivy and carb intake similar to that of Sisson? Has his view changed since the article I linked to? For example, the ApoE haplotypes seem to be pretty relevant, as evidenced here: Chris, since many people now have a lot of genetic info at their fingertips courtesy of cheap 23andMe prices, do you have any other specific genotypes to watch for wrt heart disease?
Check out the link I posted. Fat and cholesterol are very, very critical to the brain. Fat and cholesterol keep this sheath healthy. We are just the opposite of E4 carriers. The link Winslow posted above is a good resource. There was a bit of CW in that but it was still some great information there. You got my brain wheels turning, though I ended up doing just a quick search and found this: I will be researching what references I can but if Dr.
Kresser has time in the future I would love for him to look this over. Could it be due to the body needing to produce that much to ensure that enough fat, cholesterol, antioxidants, and nutrients i. Same blood sample sent to 2 different testing labs gave me different numbers. VAP went to Alabama: My IR score is I expected this since I do have a dysfunctional insulin response.